Mutation of SBDS and SH2D1A is not associated with aplastic anemia in Japanese children

Haematologica. 2007 Nov;92(11):1573. doi: 10.3324/haematol.11568.

Abstract

During the last decade, the genetic basis of inherited bone marrow failure syndromes has been identified. Recently, genetic factors predisposing to aplastic anemia (AA) have been found in a few patients with apparently acquired AA. Here we present the genetic analysis of SBDS and SH2D1A in Japanese children with AA.

Publication types

  • Letter

MeSH terms

  • Anemia, Aplastic / genetics*
  • Child
  • Humans
  • Intracellular Signaling Peptides and Proteins / genetics*
  • Japan / epidemiology
  • Mutation*
  • Proteins / genetics*
  • Signaling Lymphocytic Activation Molecule Associated Protein

Substances

  • Intracellular Signaling Peptides and Proteins
  • Proteins
  • SBDS protein, human
  • SH2D1A protein, human
  • Signaling Lymphocytic Activation Molecule Associated Protein