Expression of hypoxia-inducible factor 1alpha and 2alpha in choroidal neovascular membranes associated with age-related macular degeneration

Br J Ophthalmol. 2007 Dec;91(12):1720-1. doi: 10.1136/bjo.2006.111583.

Authors

Yuji Inoue¹, Yasuo Yanagi, Kyosuke Matsuura, Hidenori Takahashi, Yasuhiro Tamaki, Makoto Araie

Affiliation

¹ Department of Ophthalmology, University of Tokyo School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. yino-tky@umin.ac.jp

No abstract available

MeSH terms

Aged
Aged, 80 and over
Basic Helix-Loop-Helix Transcription Factors / metabolism*
Choroidal Neovascularization / etiology*
Choroidal Neovascularization / metabolism*
Choroidal Neovascularization / pathology
Endothelium, Vascular / metabolism
Female
Humans
Hypoxia-Inducible Factor 1 / metabolism*
Immunohistochemistry / methods
Macrophages / metabolism
Macular Degeneration / complications*
Male
Membranes / metabolism
Staining and Labeling
Tissue Distribution

Substances

Basic Helix-Loop-Helix Transcription Factors
Hypoxia-Inducible Factor 1
endothelial PAS domain-containing protein 1