[Leptin, leptin gene, leptin gene receptor polymorphisms and pregnancy]

Ginekol Pol. 2007 Aug;78(8):642-6.
[Article in Polish]

Abstract

The article presents information about leptin as the major metabolic hormone. The structure, localization of the hormone and its receptor have been described focusing on maturation and fertility processes. Several polymorphisms of leptin gene and its receptor have been described as potential developmental factors of pregnancy complications such as diabetes mellitus or pregnancy induced hypertension.

Publication types

  • Review

MeSH terms

  • Diabetes, Gestational / genetics*
  • Female
  • Humans
  • Hypertension, Pregnancy-Induced / genetics*
  • Leptin / metabolism*
  • Polymorphism, Genetic
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / genetics*
  • Receptors, Leptin / genetics*

Substances

  • LEPR protein, human
  • Leptin
  • Receptors, Leptin