Myeloid leukemia in children 4 years or older with Down syndrome often lacks GATA1 mutation and cytogenetics and risk of relapse are more akin to sporadic AML

Leukemia. 2008 Jul;22(7):1428-30. doi: 10.1038/sj.leu.2405060. Epub 2007 Dec 6.
No abstract available

Publication types

  • Letter

MeSH terms

  • Child
  • Child, Preschool
  • Chromosome Aberrations*
  • Down Syndrome / genetics*
  • GATA1 Transcription Factor / genetics*
  • Humans
  • Leukemia, Myeloid, Acute / genetics*
  • Mutation*
  • Recurrence
  • Risk

Substances

  • GATA1 Transcription Factor
  • GATA1 protein, human