Multiple sclerosis-like disorder in OPA1-related autosomal dominant optic atrophy

Neurology. 2008 Mar 25;70(13 Pt 2):1152-3. doi: 10.1212/01.wnl.0000289194.89359.a1. Epub 2008 Feb 20.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain / metabolism
  • Brain / pathology
  • DNA Mutational Analysis
  • Diagnosis, Differential
  • Energy Metabolism / genetics
  • GTP Phosphohydrolases / genetics*
  • Genetic Markers / genetics
  • Genetic Predisposition to Disease / genetics*
  • Genotype
  • Heterozygote
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Mitochondria / genetics
  • Mitochondria / metabolism
  • Mitochondrial Diseases / genetics
  • Mitochondrial Diseases / metabolism
  • Mitochondrial Diseases / physiopathology
  • Multiple Sclerosis / genetics*
  • Multiple Sclerosis / metabolism
  • Multiple Sclerosis / pathology*
  • Mutation / genetics
  • Nerve Fibers, Myelinated / metabolism
  • Nerve Fibers, Myelinated / pathology
  • Optic Atrophy, Autosomal Dominant / genetics*
  • Optic Atrophy, Autosomal Dominant / metabolism
  • Optic Atrophy, Autosomal Dominant / pathology*
  • Optic Nerve / metabolism
  • Optic Nerve / pathology
  • Optic Nerve / physiopathology

Substances

  • Genetic Markers
  • GTP Phosphohydrolases
  • OPA1 protein, human