Novel gain-of-function mutation in the extracellular domain of the PDGFRA gene in infant acute lymphoblastic leukemia with t(4;11)(q21;q23)

Leukemia. 2008 Dec;22(12):2279-80. doi: 10.1038/leu.2008.140. Epub 2008 Jun 12.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chromosomes, Human, Pair 11
  • Chromosomes, Human, Pair 4
  • Humans
  • Infant
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics*
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma / pathology*
  • Protein Structure, Tertiary
  • Receptor, Platelet-Derived Growth Factor alpha / chemistry
  • Receptor, Platelet-Derived Growth Factor alpha / genetics*
  • Translocation, Genetic*

Substances

  • Receptor, Platelet-Derived Growth Factor alpha