As macrophages indulge, atherosclerotic lesions bulge

Circ Res. 2008 Jun 20;102(12):1445-7. doi: 10.1161/CIRCRESAHA.108.178947.
No abstract available

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • Acetyl-CoA C-Acetyltransferase / deficiency
  • Acetyl-CoA C-Acetyltransferase / physiology
  • Animals
  • Apolipoproteins E / deficiency
  • Atherosclerosis / enzymology
  • Atherosclerosis / pathology*
  • Biological Transport / drug effects
  • Cells, Cultured / metabolism
  • Cholesterol / metabolism
  • Endocytosis
  • Esterification
  • Female
  • Foam Cells / enzymology
  • Foam Cells / pathology*
  • Humans
  • Lipoproteins / metabolism
  • Lipoproteins, LDL / metabolism
  • Lipoproteins, LDL / pharmacology
  • Macrophages / metabolism
  • Male
  • Membrane Proteins / deficiency
  • Membrane Proteins / physiology*
  • Mice
  • Mice, Knockout
  • Organelles / metabolism
  • Perilipin-2
  • Receptors, Scavenger / metabolism
  • Triglycerides / metabolism

Substances

  • Apolipoproteins E
  • Lipoproteins
  • Lipoproteins, LDL
  • Membrane Proteins
  • Perilipin-2
  • Receptors, Scavenger
  • Triglycerides
  • acetyl-LDL
  • Cholesterol
  • Acat1 protein, mouse
  • Acetyl-CoA C-Acetyltransferase