Familial systemic lupus erythematosus with hypercalcemia

Indian J Pediatr. 2008 Aug;75(8):855-7. doi: 10.1007/s12098-008-0106-6. Epub 2008 Jun 23.

Abstract

An 8-yr-old girl with familial systemic lupus erythematosus and several severe manifestations, including persistent thrombocytopenia, rapidly progressive renal failure and hepatic failure is described. The course was complicated by the occurrence of hypercalcemia, hypophosphatemia and elevated levels of parathormone, an association not previously reported in children.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Female
  • Humans
  • Hypercalcemia / complications*
  • Hypercalcemia / drug therapy
  • Hypercalcemia / pathology
  • Hypophosphatemia / blood
  • Length of Stay
  • Liver Failure / etiology
  • Lupus Erythematosus, Systemic / complications
  • Lupus Erythematosus, Systemic / drug therapy
  • Lupus Erythematosus, Systemic / genetics*
  • Methylprednisolone / administration & dosage
  • Methylprednisolone / therapeutic use
  • Parathyroid Hormone / blood
  • Prednisone / administration & dosage
  • Prednisone / therapeutic use
  • Renal Insufficiency / etiology
  • Thrombocytopenia / etiology
  • Treatment Outcome

Substances

  • Parathyroid Hormone
  • Prednisone
  • Methylprednisolone