Abstract
In patients with Guillain-Barré syndrome (GBS) soluble interleukin-2 receptor (sIL-2R) levels were elevated compared with those of patients with other neurologic diseases (OND), and of healthy controls. Smaller increases in sIL-2R levels occurred in OND patients compared to healthy subjects. Monitoring of GBS patients clearly demonstrated that decreases in sIL-2R levels correlated with clinical recovery. Thus, T-cell activation may be relevant in the pathogenesis of GBS.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Central Nervous System Diseases / blood
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Central Nervous System Diseases / physiopathology
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Family Health
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Humans
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Nervous System Diseases / blood
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Nervous System Diseases / physiopathology
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Osmolar Concentration
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Polyradiculoneuropathy / blood*
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Polyradiculoneuropathy / genetics
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Polyradiculoneuropathy / physiopathology
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Receptors, Interleukin-2 / blood*
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Reference Values
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Solubility