Slow efavirenz metabolism genotype is common in Botswana

J Acquir Immune Defic Syndr. 2008 Nov 1;49(3):336-7. doi: 10.1097/QAI.0b013e31817c1ed0.
No abstract available

Publication types

  • Letter

MeSH terms

  • Adult
  • Alkynes
  • Anti-HIV Agents / metabolism*
  • Aryl Hydrocarbon Hydroxylases / genetics*
  • Benzoxazines / metabolism*
  • Benzoxazines / therapeutic use
  • Cross-Sectional Studies
  • Cyclopropanes
  • Cytochrome P-450 CYP2B6
  • Female
  • Genotype
  • HIV Infections / drug therapy*
  • Haplotypes
  • Humans
  • Male
  • Middle Aged
  • Oxidoreductases, N-Demethylating / genetics*

Substances

  • Alkynes
  • Anti-HIV Agents
  • Benzoxazines
  • Cyclopropanes
  • Aryl Hydrocarbon Hydroxylases
  • CYP2B6 protein, human
  • Cytochrome P-450 CYP2B6
  • Oxidoreductases, N-Demethylating
  • efavirenz