Conventional MRI and NOTCH3 gene screening in sporadic CADASIL

Neurology. 2009 Feb 3;72(5):469-71. doi: 10.1212/01.wnl.0000336342.04778.2b. Epub 2008 Dec 3.
No abstract available

MeSH terms

  • Adult
  • Age of Onset
  • Aged
  • Amino Acid Substitution / genetics
  • Brain / metabolism
  • Brain / pathology*
  • Brain / physiopathology
  • CADASIL / diagnosis*
  • CADASIL / genetics*
  • CADASIL / physiopathology
  • Cerebral Arteries / metabolism
  • Cerebral Arteries / pathology
  • Cerebral Arteries / physiopathology
  • Cerebral Hemorrhage / diagnosis
  • Cerebral Hemorrhage / genetics
  • Cerebral Hemorrhage / physiopathology
  • DNA Mutational Analysis
  • Diffusion Magnetic Resonance Imaging
  • Female
  • Gene Frequency / genetics
  • Genetic Markers
  • Genetic Predisposition to Disease / genetics*
  • Genetic Testing
  • Genotype
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Middle Aged
  • Mutation / genetics*
  • Receptor, Notch3
  • Receptors, Notch / genetics*
  • Retrospective Studies
  • Young Adult

Substances

  • Genetic Markers
  • NOTCH3 protein, human
  • Receptor, Notch3
  • Receptors, Notch