A 31 year old woman with essential hypertension grade III and branch retinal vein occlusion with homozygous C677T MTHFR hyperhomocysteinemia and high Lp(a) levels

Vasiliki Katsi; Dimitris Tousoulis; Evangelos Chatzistamatiou; Emmanouil Androulakis; Georgios Moustakas; Ioannis Skiadas; Constantinos Tsioufis; Charalambos Antoniades; Christodoulos I Stefanadis; Ioannis E Kallikazaros

doi:10.1016/j.ijcard.2008.12.015

A 31 year old woman with essential hypertension grade III and branch retinal vein occlusion with homozygous C677T MTHFR hyperhomocysteinemia and high Lp(a) levels

Int J Cardiol. 2010 Sep 3;143(3):e42-4. doi: 10.1016/j.ijcard.2008.12.015. Epub 2009 Jan 9.

Authors

Vasiliki Katsi, Dimitris Tousoulis, Evangelos Chatzistamatiou, Emmanouil Androulakis, Georgios Moustakas, Ioannis Skiadas, Constantinos Tsioufis, Charalambos Antoniades, Christodoulos I Stefanadis, Ioannis E Kallikazaros

PMID: 19135738
DOI: 10.1016/j.ijcard.2008.12.015

Abstract

We report a 31-year old woman with essential hypertension grade III and history of branch retinal vein occlusion in the setting of hyperhomocysteinemia due to homozygous MTHFR gene mutation and elevated Lp(a). The patient was treated successfully with antihypertensive treatment, acetylsalicylic acid and multivitamin complex supplementation.

Publication types

Case Reports
Letter

MeSH terms

Adult
Antihypertensive Agents / therapeutic use
Aspirin / therapeutic use
Female
Humans
Hyperhomocysteinemia / complications*
Hyperhomocysteinemia / genetics*
Hyperhomocysteinemia / metabolism
Hypertension / complications*
Hypertension / drug therapy
Lipoprotein(a) / blood
Methylenetetrahydrofolate Reductase (NADPH2) / genetics*
Point Mutation
Retinal Vein Occlusion / drug therapy
Retinal Vein Occlusion / etiology*
Vitamins / therapeutic use

Substances

Antihypertensive Agents
Lipoprotein(a)
Vitamins
Methylenetetrahydrofolate Reductase (NADPH2)
Aspirin