Negative prognostic impact of PTEN mutation in pediatric T-cell acute lymphoblastic leukemia

Leukemia. 2010 Jan;24(1):239-42. doi: 10.1038/leu.2009.209. Epub 2009 Oct 15.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child
  • Exons
  • Humans
  • Mutation*
  • PTEN Phosphohydrolase / genetics*
  • Phosphatidylinositol 3-Kinases / physiology
  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / genetics*
  • Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / mortality
  • Prognosis
  • Proto-Oncogene Proteins c-akt / physiology

Substances

  • Phosphatidylinositol 3-Kinases
  • Proto-Oncogene Proteins c-akt
  • PTEN Phosphohydrolase
  • PTEN protein, human