Abstract
In this issue of Molecular Cell, Deans and West (2009) reveal the molecular basis of the phenotypic similarities between Fanconi Anemia (FA) and Bloom's Syndrome, identifying FANCM as the anchor for both FA and Bloom's complexes at the site of the DNA interstrand crosslink.
2009 Elsevier Inc.
Publication types
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Comment
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Research Support, N.I.H., Extramural
MeSH terms
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Bloom Syndrome* / genetics
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Bloom Syndrome* / metabolism
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DNA Damage
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DNA Helicases / genetics
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DNA Helicases / metabolism*
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DNA Repair
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Fanconi Anemia* / genetics
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Fanconi Anemia* / metabolism
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Humans
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Phenotype
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RecQ Helicases / genetics
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RecQ Helicases / metabolism
Substances
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Bloom syndrome protein
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FANCM protein, human
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DNA Helicases
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RecQ Helicases