Large cell/neuroendocrine carcinoma

Russell Gollard; Sejal Jhatakia; Max Elliott; Michael Kosty

doi:10.1016/j.lungcan.2009.12.011

Large cell/neuroendocrine carcinoma

Lung Cancer. 2010 Jul;69(1):13-8. doi: 10.1016/j.lungcan.2009.12.011. Epub 2010 Feb 4.

Authors

Russell Gollard¹, Sejal Jhatakia, Max Elliott, Michael Kosty

Affiliation

¹ Cancer & Blood Specialists of Nevada, 58 N. Pecos Road, Henderson, NV 89074, USA. rgollard@hotmail.com

PMID: 20133008
DOI: 10.1016/j.lungcan.2009.12.011

Abstract

Large cell neuroendocrine tumors of the lung represent a recently reclassified subtype of lung cancer with features of both small cell and non-small cell lung cancer. We review diagnostic difficulties, typical presentations, and the natural history of this tumor. We review treatment data, and suggest that as in more common types of lung cancer, multi-modality therapy may be the most promising course of treatment.

Publication types

Review

MeSH terms

Animals
Carcinoma, Large Cell / diagnosis*
Carcinoma, Large Cell / pathology
Carcinoma, Large Cell / physiopathology
Carcinoma, Large Cell / therapy
Carcinoma, Neuroendocrine / diagnosis*
Carcinoma, Neuroendocrine / pathology
Carcinoma, Neuroendocrine / physiopathology
Carcinoma, Neuroendocrine / therapy
Clinical Trials as Topic
Combined Modality Therapy
Diagnosis, Differential
Humans
Lung Neoplasms / diagnosis*
Lung Neoplasms / pathology
Lung Neoplasms / physiopathology
Lung Neoplasms / therapy