Abstract
We examined the association between diabetic retinopathy and monocyte chemoattractant protein (MCP)-1 A-2518G polymorphism in 3802 Japanese type 2 diabetic subjects. The prevalence of diabetic retinopathy was higher as the number of G alleles increased, suggesting that the G allele of this polymorphism is a susceptibility allele for diabetic retinopathy.
MeSH terms
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Aged
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Asian People / genetics*
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Asian People / statistics & numerical data
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Chemokine CCL2 / genetics*
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Diabetes Mellitus, Type 2 / ethnology*
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Diabetes Mellitus, Type 2 / genetics*
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Diabetic Retinopathy / ethnology*
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Diabetic Retinopathy / genetics*
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Female
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Genetic Predisposition to Disease / ethnology
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Genotype
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Heptavalent Pneumococcal Conjugate Vaccine
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Humans
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Japan / epidemiology
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Logistic Models
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Male
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Middle Aged
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Multivariate Analysis
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Pneumococcal Vaccines
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Polymorphism, Genetic
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Risk Factors
Substances
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CCL2 protein, human
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Chemokine CCL2
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Heptavalent Pneumococcal Conjugate Vaccine
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Pneumococcal Vaccines