During the last decade, mutations in a growing number of genes have been found to cause monogenic forms of Parkinson's disease (PD). Moreover, many studies shed light on their contribution to sporadic variants of PD. Since hyperechogenicity of the substantia nigra (SN) represents a characteristic hallmark of sporadic PD questions arise concerning the echo pattern of monogenic forms of this disorder on TCS.
Copyright 2010 Elsevier Inc. All rights reserved.