Abstract
We report a patient with systemic lupus erythematosus (SLE) who showed periodic peritonitis with spontaneous remission. She showed compound heterozygous mutations in the MEFV gene, leading to the diagnosis of familial Mediterranean fever (FMF). Oral colchicine successfully reduced the severity and frequency of her peritonitis. SLE occasionally manifests abdominal symptoms, but in cases with periodic peritonitis, associated FMF should be considered as a possible cause.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Abdominal Pain / etiology*
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Adult
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Chlamydia Infections / diagnosis
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Colchicine / therapeutic use
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Cytoskeletal Proteins / genetics
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Diagnosis, Differential
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Familial Mediterranean Fever / complications*
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Familial Mediterranean Fever / diagnosis
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Familial Mediterranean Fever / genetics
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Female
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Heterozygote
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Humans
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Lupus Erythematosus, Systemic / complications*
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Mutation, Missense
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Peripheral Arterial Disease / etiology
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Peritonitis / drug therapy
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Peritonitis / etiology*
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Pyrin
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Recurrence
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Toes / blood supply
Substances
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Cytoskeletal Proteins
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MEFV protein, human
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Pyrin
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Colchicine