Low-renin hypertension of childhood

Alan A Parsa; Maria I New

doi:10.1016/j.ecl.2011.01.004

Low-renin hypertension of childhood

Endocrinol Metab Clin North Am. 2011 Jun;40(2):369-77, viii. doi: 10.1016/j.ecl.2011.01.004.

Authors

Alan A Parsa¹, Maria I New

Affiliation

¹ Department of Pediatrics, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1198, New York, NY 10029, USA.

PMID: 21565672
DOI: 10.1016/j.ecl.2011.01.004

Abstract

Low-renin hypertension occurs in children as a result of several genetic mutations that cause mineralocorticoid excess or excess stimulation of the mineralocorticoid receptor. This article discusses the genetic disorders that cause low-renin hypertension.

MeSH terms

Adrenal Hyperplasia, Congenital / genetics
Adrenal Hyperplasia, Congenital / physiopathology
Adrenal Hyperplasia, Congenital / therapy
Child
Child, Preschool
Female
Humans
Hyperaldosteronism / genetics
Hyperaldosteronism / physiopathology
Hyperaldosteronism / therapy
Hypertension / blood*
Hypertension / genetics*
Hypertension / physiopathology
Infant
Infant, Newborn
Male
Mineralocorticoid Excess Syndrome, Apparent / genetics
Mineralocorticoid Excess Syndrome, Apparent / physiopathology
Mineralocorticoid Excess Syndrome, Apparent / therapy
Renin / blood*

Substances

Renin

Supplementary concepts

Adrenal hyperplasia, congenital, type 5
Congenital adrenal hyperplasia due to 11-Beta-hydroxylase deficiency