Abstract
We present 2 patients with hyperferritinemia, increased liver iron and hemochromatosis-associated HFE genotypes. At diagnosis, both patients had chronic anemia that prevented initiation of phlebotomy. Iron chelation with deferasirox proved to be a safe and effective means of substantially lowering ferritin levels.
Copyright © 2011 S. Karger AG, Basel.
MeSH terms
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Aged
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Benzoates / therapeutic use*
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Chelation Therapy*
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Deferasirox
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Female
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Genotype
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Hemochromatosis / drug therapy*
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Hemochromatosis Protein
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Histocompatibility Antigens Class I / genetics*
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Humans
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Iron Chelating Agents / therapeutic use*
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Male
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Membrane Proteins / genetics*
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Treatment Outcome
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Triazoles / therapeutic use*
Substances
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Benzoates
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HFE protein, human
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Hemochromatosis Protein
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Histocompatibility Antigens Class I
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Iron Chelating Agents
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Membrane Proteins
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Triazoles
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Deferasirox