Abstract
We recently encountered an unusual case of Composite lymphoma (CL) in the anterior mediastinum arising in a 37-year-old woman who presented initially with continuous pain in the right shoulder and chest. The woman had been suffered from continuous pain for three months before she went to our department of cardiovascular surgery. Chest computed tomography scan revealed the oval space-occupying lesion of anterior mediastinum. Surgery was performed and the disease was diagnosed pathologically as CL which composed of nodular sclerosing Hodgkin lymphoma and diffuse large B-cell lymphoma, via hematoxylin-eosin (H&E), immunohistochemical staining and in situ hybridization.
MeSH terms
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Adult
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Antineoplastic Combined Chemotherapy Protocols / therapeutic use
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Combined Modality Therapy
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Composite Lymphoma / diagnosis*
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Composite Lymphoma / genetics
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Composite Lymphoma / therapy
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Cyclophosphamide / therapeutic use
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Disease-Free Survival
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Doxorubicin / therapeutic use
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Female
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Hodgkin Disease / diagnosis*
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Hodgkin Disease / genetics
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Hodgkin Disease / therapy
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Humans
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In Situ Hybridization
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Lymphoma, Large B-Cell, Diffuse / diagnosis*
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Lymphoma, Large B-Cell, Diffuse / genetics
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Lymphoma, Large B-Cell, Diffuse / therapy
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Mediastinal Neoplasms / diagnosis*
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Mediastinal Neoplasms / genetics
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Mediastinal Neoplasms / therapy
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Prednisone / therapeutic use
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Radiotherapy, Adjuvant
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Sclerosis
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Tomography, X-Ray Computed
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Vincristine / therapeutic use
Substances
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Vincristine
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Doxorubicin
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Cyclophosphamide
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Prednisone