Mastoiditis secondary to metastatic lung carcinoma: case report and literature review

J Laryngol Otol. 2011 Nov;125(11):1173-5. doi: 10.1017/S0022215111001666. Epub 2011 Aug 22.

Abstract

Objective: We present a case report and systematic review of acute mastoiditis caused by metastatic lung cancer.

Case report: A 62-year-old woman developed acute mastoiditis as a complication of otitis media. Cortical mastoidectomy revealed deposits of metastatic non-small cell lung carcinoma around the sigmoid sinus. The patient had previously received treatment for lung cancer, but was thought to be in remission.

Discussion: A literature review confirmed that this is the first reported case of mastoiditis caused by metastatic lung cancer. Only four similar case reports were identified: two caused by breast carcinoma, one by renal cell carcinoma and one by cholangiocarcinoma. Post-mortem histopathological studies suggest that temporal bone metastasis occurs in 22 per cent of oncology cases.

Conclusion: This is the first reported case of mastoiditis caused by metastatic lung cancer. Metastasis to the temporal bone is not uncommon, but rarely causes mastoiditis.

Publication types

  • Case Reports
  • Review
  • Systematic Review

MeSH terms

  • Biopsy
  • Carcinoma, Non-Small-Cell Lung / pathology*
  • Earache / diagnosis
  • Female
  • Humans
  • Lung Neoplasms / pathology*
  • Magnetic Resonance Imaging
  • Mastoid / pathology*
  • Mastoid / surgery
  • Mastoiditis / diagnosis*
  • Mastoiditis / etiology
  • Mastoiditis / therapy
  • Middle Aged
  • Middle Ear Ventilation
  • Necrosis
  • Otitis Media with Effusion / complications*
  • Otitis Media with Effusion / drug therapy
  • Skull Neoplasms / diagnosis
  • Skull Neoplasms / secondary*
  • Tomography, X-Ray Computed
  • Treatment Outcome