The -2518A/G polymorphism in the monocyte chemoattractant protein-1 (MCP-1) gene and diabetes risk: a meta-analysis

Yonggang Zhang; Jie Zhang; Can Tian; Narenqimuge; Yao Deng; Yuliang Zhao; Hong Fan; Jin Huang

doi:10.1016/j.diabres.2011.09.005

The -2518A/G polymorphism in the monocyte chemoattractant protein-1 (MCP-1) gene and diabetes risk: a meta-analysis

Diabetes Res Clin Pract. 2011 Dec;94(3):e89-92. doi: 10.1016/j.diabres.2011.09.005. Epub 2011 Oct 10.

Authors

Yonggang Zhang¹, Jie Zhang, Can Tian, Narenqimuge, Yao Deng, Yuliang Zhao, Hong Fan, Jin Huang

Affiliation

¹ West China Medical School/West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.

PMID: 21992868
DOI: 10.1016/j.diabres.2011.09.005

Abstract

We conducted a meta-analysis to investigate the association between the -2518A/G polymorphism in the MCP-1 gene and the risk of diabetes. Ten case-control studies were included in this meta-analysis. Results indicated this polymorphism may be a risk factor for diabetes in Caucasians. Future studies are needed to validate our conclusions.

Publication types

Meta-Analysis
Research Support, Non-U.S. Gov't

MeSH terms

Case-Control Studies
Chemokine CCL2 / genetics*
Diabetes Mellitus / genetics*
Genetic Predisposition to Disease
Humans
Polymorphism, Genetic / genetics*
Prognosis
Risk Factors

Substances

CCL2 protein, human
Chemokine CCL2