Abstract
The authors represent results of studies concerning distribution of CPOX and TNF-alpha genes in workers engaged into chemical production. Findings are peculiarities of genetic polymorphism of CPOX gene and TNF gene, and their association with biologic media contamination with methylated phenols (m-cresol) and apoptosis disorders.
MeSH terms
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Adult
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Apoptosis / genetics
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Chemical Industry
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Coproporphyrinogen Oxidase / genetics*
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Cresols / toxicity
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Humans
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Middle Aged
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Occupational Diseases / chemically induced
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Occupational Diseases / enzymology
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Occupational Diseases / genetics*
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Occupational Exposure / adverse effects*
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Polymorphism, Genetic*
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Tumor Necrosis Factor-alpha / genetics*
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Young Adult
Substances
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Cresols
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Tumor Necrosis Factor-alpha
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4-cresol
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Coproporphyrinogen Oxidase