Abstract
This report describes a transient hypertrophic cardiomyopathy with right-ventricle outlet tract obstruction (RVOTO) induced by perinatal stress due to a major surgical procedure in a female newborn with congenital abnormalities. On day 10, she presented with heart failure, abnormal B-type natriuretic peptide (BNP), and an echocardiogram showing normal wall thickness. An in-hospital follow-up echocardiogram showed biventricular hypertrophy and RVOTO. At discharge, the infant was asymptomatic, with a normal echocardiogram and BNP. Transient RVOTO triggered by surgical stress and abnormal BNP have not been reported previously. Pathophysiology, the role of BNP, and clinical characteristics are discussed.
MeSH terms
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Abnormalities, Multiple / diagnosis
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Abnormalities, Multiple / surgery*
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Apgar Score
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Biomarkers / blood
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Cardiomyopathy, Hypertrophic / diagnostic imaging
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Cardiomyopathy, Hypertrophic / physiopathology
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Cardiomyopathy, Hypertrophic / therapy*
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Cesarean Section
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Combined Modality Therapy
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Echocardiography, Doppler
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Electrocardiography / methods
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Female
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Follow-Up Studies
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Humans
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Hydrocephalus / diagnosis
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Hydrocephalus / surgery
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Infant, Newborn
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Meningomyelocele / diagnosis
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Meningomyelocele / surgery
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Natriuretic Peptide, Brain / analysis
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Natriuretic Peptide, Brain / metabolism*
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Risk Assessment
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Spinal Dysraphism / diagnosis
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Spinal Dysraphism / surgery
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Takotsubo Cardiomyopathy / diagnostic imaging*
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Takotsubo Cardiomyopathy / physiopathology
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Takotsubo Cardiomyopathy / therapy*
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Treatment Outcome
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Ultrasonography, Prenatal / methods
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Ventricular Outflow Obstruction / diagnostic imaging*
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Ventricular Outflow Obstruction / physiopathology
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Ventricular Outflow Obstruction / therapy
Substances
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Biomarkers
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Natriuretic Peptide, Brain