Abstract
Restless legs syndrome is a curious neurological disorder of unknown aetiology. A new study has found that Drosophila mutants in the fly homologue of a human gene, BTBD9, that has been implicated as a risk factor for restless legs display important features of the syndrome.
Copyright © 2012 Elsevier Ltd. All rights reserved.
MeSH terms
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Animals
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Brain / metabolism*
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Carrier Proteins / genetics*
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Dopamine / metabolism*
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Drosophila Proteins / genetics*
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Humans
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Iron / metabolism*
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Restless Legs Syndrome / genetics*
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Restless Legs Syndrome / physiopathology*
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Sleep Deprivation / genetics*
Substances
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BTBD9 protein, Drosophila
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Carrier Proteins
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Drosophila Proteins
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Iron
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Dopamine