Transformation of refractory anemia with excess of blasts into acute myelogenous leukemia with Ph-negative chronic myelogenous leukemia-like characteristics

Am J Hematol. 1990 Jan;33(1):69-71. doi: 10.1002/ajh.2830330114.

Abstract

We report a 56 year old patient with acute myelogenous leukemia (FAB classification: M2), in whom the number of mature myeloid cells similar to those seen in Ph-negative chronic myelogenous leukemia increased markedly 2 months after the diagnosis of refractory anemia with excess of blasts (RAEB). This is a rare case of leukemic evolution as a terminal event of RAEB.

Publication types

  • Case Reports

MeSH terms

  • Anemia, Refractory, with Excess of Blasts / complications*
  • Chromosome Banding
  • Chromosomes, Human, Pair 13
  • Chromosomes, Human, Pair 5
  • Humans
  • Leukemia, Myeloid, Acute / genetics
  • Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative / etiology*
  • Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative / genetics
  • Male
  • Middle Aged
  • Translocation, Genetic