Cerebellar malignant fibrous histiocytoma

Indian J Pathol Microbiol. 2012 Jul-Sep;55(3):402-5. doi: 10.4103/0377-4929.101759.

Abstract

Malignant fibrous histiocytoma (MFH) is uncommon within the central nervous system. MFH is a malignant tumor composed of a mixture of fibroblastic and histiocytic cells, and is also known as pleomorphic fibrous xanthoma, malignant fibrous xanthoma, and pleomorphic fibrous histiocytoma. It is a pleomorphic sarcoma originally found in soft tissue and there are few reported cases within the central nervous system, in particular the cerebellum. To the best of my knowledge, this is third case arising from the cerebellum. This tumor is difficult to diagnose and may be difficult to treat.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antigens, CD / analysis
  • Antigens, Differentiation, Myelomonocytic / analysis
  • Cerebellar Neoplasms / diagnosis*
  • Cerebellar Neoplasms / pathology*
  • Head / diagnostic imaging
  • Histiocytoma, Malignant Fibrous / diagnosis*
  • Histiocytoma, Malignant Fibrous / pathology*
  • Histocytochemistry
  • Humans
  • Immunohistochemistry
  • Keratins / analysis
  • Magnetic Resonance Imaging
  • Male
  • Microscopy
  • Radiography
  • Vimentin / analysis

Substances

  • Antigens, CD
  • Antigens, Differentiation, Myelomonocytic
  • CD68 antigen, human
  • Vimentin
  • Keratins