New pathogenic mechanisms in Burkitt lymphoma

Elias Campo

doi:10.1038/ng.2476

New pathogenic mechanisms in Burkitt lymphoma

Nat Genet. 2012 Dec;44(12):1288-9. doi: 10.1038/ng.2476.

Author

Elias Campo¹

Affiliation

¹ Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain. ecampo@clinic.ub.es

PMID: 23192177
DOI: 10.1038/ng.2476

Abstract

Two studies in this issue identify the landscape of somatic mutations in Burkitt lymphoma and highlight the pathogenic and clinical relevance of inactivating mutations of ID3, an inhibitor of the TCF3 transcription factor.

Publication types

News

MeSH terms

Burkitt Lymphoma / genetics
Burkitt Lymphoma / pathology*
Humans
Inhibitor of Differentiation Proteins / genetics
Mutation
Neoplasm Proteins / genetics

Substances

Inhibitor of Differentiation Proteins
Neoplasm Proteins
ID3 protein, human