Cyclin D1-negative mantle cell lymphoma

Blood. 2013 Feb 21;121(8):1249-50. doi: 10.1182/blood-2013-01-475954.

Abstract

In this issue of Blood, Salaverria et al report that more than half of Cyclin D1- (CCND1) negative SOX11-positive mantle cell lymphoma (MCL) had CCND2 gene rearrangement predominantly with immunoglobulin (IG) light chain genes.(1)

Publication types

  • Comment

MeSH terms

  • Cyclin D1 / genetics*
  • Cyclin D2 / genetics*
  • Female
  • Gene Rearrangement / genetics*
  • Humans
  • Lymphoma, Mantle-Cell / genetics*
  • Lymphoma, Mantle-Cell / pathology*
  • Male

Substances

  • CCND1 protein, human
  • CCND2 protein, human
  • Cyclin D2
  • Cyclin D1