RETRACTED: Increased neuroinflammatory and arachidonic acid cascade markers, and reduced synaptic proteins, in the postmortem frontal cortex from schizophrenia patients

Schizophr Res. 2013 Jun;147(1):24-31. doi: 10.1016/j.schres.2013.02.017. Epub 2013 Apr 6.

Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the Editors. The National Institutes of Health has found that Dr. Jagadeesh S. Rao engaged in research misconduct by falsifying data. Data in Figures 1A, 1E, 3E and 3F were falsified. Dr. Rao was solely responsible for the falsification. None of the other authors are implicated in any way.

Publication types

  • Research Support, N.I.H., Intramural

MeSH terms

  • Adult
  • Aged
  • Analysis of Variance
  • Arachidonic Acid / metabolism*
  • Cytokines / genetics
  • Cytokines / metabolism*
  • Female
  • Frontal Lobe / metabolism*
  • Gene Expression Regulation / physiology*
  • HLA-DR Antigens / metabolism
  • Humans
  • Male
  • Microglia / metabolism
  • Middle Aged
  • Nerve Tissue Proteins / metabolism*
  • Nitric Oxide Synthase Type II / chemical synthesis
  • Nitric Oxide Synthase Type II / genetics
  • Nitric Oxide Synthase Type II / metabolism
  • Postmortem Changes
  • Proto-Oncogene Proteins c-fos / genetics
  • Proto-Oncogene Proteins c-fos / metabolism
  • RNA, Messenger
  • Receptors, N-Methyl-D-Aspartate
  • Schizophrenia / complications*
  • Schizophrenia / pathology*

Substances

  • Cytokines
  • HLA-DR Antigens
  • Nerve Tissue Proteins
  • Proto-Oncogene Proteins c-fos
  • RNA, Messenger
  • Receptors, N-Methyl-D-Aspartate
  • Arachidonic Acid
  • Nitric Oxide Synthase Type II