Abstract
We describe a cutaneous abscess caused by catalase-negative methicillin-susceptible Staphylococcus aureus subsp. aureus in a patient who was concomitantly colonized with virulent USA300 methicillin-resistant S. aureus (MRSA). Sequencing of the katA gene demonstrated a thymine insertion leading to a frameshift mutation and premature truncation of catalase to 21 amino acids.
Publication types
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Case Reports
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Abscess / diagnosis*
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Abscess / microbiology*
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Catalase / genetics*
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Codon, Nonsense
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Frameshift Mutation
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Humans
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Male
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Sequence Analysis, DNA
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Staphylococcal Skin Infections / diagnosis*
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Staphylococcal Skin Infections / microbiology*
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Staphylococcus aureus / enzymology*
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Staphylococcus aureus / isolation & purification*
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Young Adult