Vertebral aspergillosis in a patient with autosomal-dominant hyper-IgE syndrome

Clin Vaccine Immunol. 2014 Jan;21(1):107-9. doi: 10.1128/CVI.00529-13. Epub 2013 Nov 6.

Abstract

We present a report of an autosomal-dominant hyper-IgE syndrome patient with vertebral aspergillosis. Early diagnosis and antifungal therapy with surgery are crucial for improving the outcome of this aggressive condition.

Publication types

  • Case Reports

MeSH terms

  • Antifungal Agents / therapeutic use
  • Aspergillosis / diagnosis*
  • Aspergillosis / drug therapy
  • Aspergillosis / pathology*
  • Aspergillosis / surgery
  • Child
  • Debridement
  • Histocytochemistry
  • Humans
  • Job Syndrome / complications*
  • Magnetic Resonance Imaging
  • Male
  • Microscopy
  • Radiography
  • STAT3 Transcription Factor / deficiency*
  • Spine / diagnostic imaging
  • Spine / pathology*

Substances

  • Antifungal Agents
  • STAT3 Transcription Factor

Supplementary concepts

  • Hyper-Ige Recurrent Infection Syndrome, Autosomal Dominant