Functional imaging in lung cancer

Clin Physiol Funct Imaging. 2014 Sep;34(5):340-55. doi: 10.1111/cpf.12104. Epub 2013 Dec 1.

Abstract

Lung cancer represents an increasingly frequent cancer diagnosis worldwide. An increasing awareness on smoking cessation as an important mean to reduce lung cancer incidence and mortality, an increasing number of therapy options and a steady focus on early diagnosis and adequate staging have resulted in a modestly improved survival. For early diagnosis and precise staging, imaging, especially positron emission tomography combined with CT (PET/CT), plays an important role. Other functional imaging modalities such as dynamic contrast-enhanced CT (DCE-CT) and diffusion-weighted MR imaging (DW-MRI) have demonstrated promising results within this field. The purpose of this review is to provide the reader with a brief and balanced introduction to these three functional imaging modalities and their current or potential application in the care of patients with lung cancer.

Keywords: diagnosis; diffusion magnetic resonance imaging/methods; lung neoplasms/diagnosis; neoplasm staging; positron emission tomography and computed tomography/methods; tomography, x-ray computed/methods.

Publication types

  • Review

MeSH terms

  • Diagnostic Imaging / methods*
  • Diffusion Magnetic Resonance Imaging
  • Humans
  • Lung Neoplasms / diagnosis*
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / pathology
  • Multimodal Imaging
  • Neoplasm Staging
  • Positron-Emission Tomography
  • Predictive Value of Tests
  • Tomography, X-Ray Computed