Surgical experience for prolapse of both atrioventricular valves in a patient with filamin A mutation

Takaya Hoashi; Isao Shiraishi; Hajime Ichikawa

doi:10.1017/S1047951114000122

Surgical experience for prolapse of both atrioventricular valves in a patient with filamin A mutation

Cardiol Young. 2015 Feb;25(2):365-7. doi: 10.1017/S1047951114000122. Epub 2014 Feb 13.

Authors

Takaya Hoashi¹, Isao Shiraishi², Hajime Ichikawa¹

Affiliations

¹ 1Department of Pediatric Cardiovascular Surgery,National Cerebral and Cardiovascular Center,Suita,Osaka,Japan.
² 2Department of Pediatric Cardiology,National Cerebral and Cardiovascular Center,Suita,Osaka,Japan.

PMID: 24521555
DOI: 10.1017/S1047951114000122

Abstract

A 21-year-old man underwent mitral valve replacement and tricuspid annuloplasty for severe mitral regurgitation and moderate tricuspid regurgitation. Until the operation, he had been treated for hypermobility type Ehlers-Danlos syndrome. Gene examination revealed a mutation in filamin A gene, which is the gene responsible for X-linked myxomatous valvular dystrophy.

Keywords: paediatric.

Publication types

Case Reports

MeSH terms

Cardiac Valve Annuloplasty / methods*
Filamins / genetics*
Genetic Diseases, X-Linked / genetics*
Heart Defects, Congenital / genetics*
Heart Valve Prosthesis Implantation / methods*
Humans
Male
Mitral Valve Insufficiency / genetics
Mitral Valve Insufficiency / surgery*
Mitral Valve Prolapse / genetics*
Myxoma / genetics*
Tricuspid Valve Insufficiency / genetics
Tricuspid Valve Insufficiency / surgery*
Young Adult

Substances

Filamins

Supplementary concepts

Cardiac valvular dysplasia, X-linked