Therapeutic opportunities for medulloblastoma come of age

James M Olson

doi:10.1016/j.ccr.2014.03.003

Therapeutic opportunities for medulloblastoma come of age

Cancer Cell. 2014 Mar 17;25(3):267-9. doi: 10.1016/j.ccr.2014.03.003.

Author

James M Olson¹

Affiliation

¹ Fred Hutchinson Cancer Research Center and Seattle Children's Hospital, Seattle WA 98109, USA. Electronic address: jolson@fhcrc.org.

Abstract

In this issue of Cancer Cell, Kool and colleagues reveal clear genetically defined subclasses of the sonic hedgehog (SHH) subclass of medulloblastoma. This molecular dissection of the SHH subclass is not simply a cutting-edge advance; the data have profound impact on clinical trial design and decision-making.

Publication types

Comment

MeSH terms

Animals
Clonal Evolution / genetics*
Genetic Variation / genetics*
Humans
Leukemia, Myeloid, Acute / genetics*

Abstract

Publication types

MeSH terms

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