Abstract
In this issue of Blood, Allinne et al propose the nucleolin-dependent activation of the translocated CCND1 allele in mantle cell lymphoma (MCL) because of its relocalization to a transcriptionally favorable area in the perinucleolar region.
MeSH terms
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Cell Nucleolus / metabolism*
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Cyclin D1 / metabolism*
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Gene Expression Regulation, Neoplastic*
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Humans
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Lymphoma, Mantle-Cell / genetics*
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Nucleolin
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Phosphoproteins / metabolism*
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RNA-Binding Proteins / metabolism*
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Transcriptional Activation*
Substances
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Phosphoproteins
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RNA-Binding Proteins
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Cyclin D1