MET as a target in papillary renal cell carcinoma

Clin Cancer Res. 2014 Jul 1;20(13):3361-3. doi: 10.1158/1078-0432.CCR-14-0690. Epub 2014 May 8.

Abstract

The biology underlying papillary renal cell carcinoma (pRCC) is largely unknown, and no specific therapies have been developed for advanced disease. The elucidation of the MET pathway status in types I and II pRCC may help to select patients who are more likely to benefit from MET inhibitors.

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Carcinoma, Papillary / genetics*
  • Female
  • Humans
  • Kidney Neoplasms / genetics*
  • Kidney Neoplasms / pathology*
  • Male
  • Proto-Oncogene Proteins c-met / genetics*

Substances

  • Proto-Oncogene Proteins c-met