Do certain drugs cause the megacystis-microcolon-intestinal hypoperistalsis syndrome

Turk J Pediatr. 1989 Jul-Sep;31(3):253-6.

Abstract

A case of megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) in the offspring of a mother who had ingested scopolamine, trimethoprim-sulfadiazine and dipyrone during pregnancy is presented. In order to determine whether a relationship exists between maternal drug ingestion and MMIHS, the need for further experimental studies is stressed.

Publication types

  • Case Reports

MeSH terms

  • Abnormalities, Drug-Induced / etiology*
  • Abnormalities, Drug-Induced / pathology
  • Abnormalities, Drug-Induced / surgery
  • Colon / abnormalities*
  • Dipyrone / adverse effects*
  • Humans
  • Infant, Newborn
  • Intestines / abnormalities*
  • Male
  • Scopolamine / adverse effects*
  • Trimethoprim, Sulfamethoxazole Drug Combination / adverse effects*

Substances

  • Dipyrone
  • Trimethoprim, Sulfamethoxazole Drug Combination
  • Scopolamine