Abstract
In this issue of Blood, Shochat et al report mutations in receptors for interleukin-7 (IL-7) and thymic stromal lymphopoietin (TSLP), resulting in a novel dimerization mechanism that drives acute lymphoblastic leukemias.
MeSH terms
-
Animals
-
Female
-
Humans
-
Mutation*
-
Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics*
-
Receptors, Cytokine / genetics*
-
Receptors, Interleukin-7 / genetics*
Substances
-
CRLF2 protein, human
-
Receptors, Cytokine
-
Receptors, Interleukin-7