Use of transrenal DNA for the diagnosis of extrapulmonary tuberculosis in children: a case of tubercular otitis media

J Clin Microbiol. 2015 Jan;53(1):336-8. doi: 10.1128/JCM.02548-14. Epub 2014 Oct 22.

Abstract

The diagnosis of tuberculosis (TB) is difficult in children, especially for smear-negative pulmonary and extrapulmonary TB, which are common at this age. We report an 11-year-old girl with TB otitis media with negative smear microscopy and Xpert MTB/RIF but positive Mycobacterium tuberculosis-specific transrenal DNA (Tr-MTB-DNA) test results and culture for M. tuberculosis.

Publication types

  • Case Reports

MeSH terms

  • Antitubercular Agents / therapeutic use
  • Child
  • DNA, Bacterial* / genetics
  • DNA, Bacterial* / urine
  • Female
  • Humans
  • Otitis Media* / diagnosis
  • Otitis Media* / drug therapy
  • Otitis Media* / microbiology
  • Tuberculosis* / diagnosis
  • Tuberculosis* / drug therapy
  • Tuberculosis* / microbiology

Substances

  • Antitubercular Agents
  • DNA, Bacterial