To explore the correlations of abnormal pulse pressure (PP) with the cardiovascular risk factors and cardiac functions by analyzing the distributions of abnormal PP in Han adults aged 18-74 years in Hebei, Zhejiang, and Guangxi province to provide evidence for health management. A cross-sectional study was carried out in three provinces of China. Multi-phase, stratified, unequal proportional and cluster sampling was adopted to investigate the data obtained from 12,795 Han adults aged 18-74 years. The prevalence of cases with abnormal PP in the three provinces was 6.7 %. Abnormal PP was significantly associated with a number of cardiovascular risk factors including location, age, gender, and education (P < 0.05). Results from multivariable logistic regression analysis showed that abnormal PP was positively associated with age and BMI. Compared with the normal subjects, there was a statistically significant difference in the mean of high-normal blood pressure, IFG divided by gender and LCW (P < 0.05). There was no significant difference in the mean of high-normal TC, TG, and LDL-C and low-normal HDL-C (P > 0.05). Age has also been found to be a statistically significant factor (P < 0.05). Abnormal PP was common in Chinese Han adults aged 18-74 years, which was independently associated with cardiovascular risk factors and cardiac functions. Health management for Han adults with abnormal PP was strongly suggested.