Abstract
An MAFG-containing corepressor complex induces CIMP in BRAF(V600E)-positive colorectal cancer.
©2014 American Association for Cancer Research.
MeSH terms
-
Adaptor Proteins, Signal Transducing / genetics
-
Adaptor Proteins, Signal Transducing / metabolism
-
Colorectal Neoplasms / genetics*
-
Colorectal Neoplasms / metabolism
-
CpG Islands*
-
Humans
-
MafG Transcription Factor / metabolism*
-
Methylation
-
MutL Protein Homolog 1
-
Mutation
-
Nuclear Proteins / genetics
-
Nuclear Proteins / metabolism
-
Proto-Oncogene Proteins B-raf / genetics*
-
Proto-Oncogene Proteins B-raf / metabolism
-
Repressor Proteins / metabolism*
Substances
-
Adaptor Proteins, Signal Transducing
-
MAFG protein, human
-
MLH1 protein, human
-
MafG Transcription Factor
-
Nuclear Proteins
-
Repressor Proteins
-
BRAF protein, human
-
Proto-Oncogene Proteins B-raf
-
MutL Protein Homolog 1