Cerebral venous thrombosis with subarachnoid hemorrhage: a case report

Clin Med Res. 2015 Mar;13(1):40-3. doi: 10.3121/cmr.2014.1225. Epub 2014 Nov 7.

Abstract

Cerebral venous thrombosis (CVT) presenting as subarachnoid hemorrhage (SAH) is infrequent. We present the case of a man with CVT of the right transverse sinus who presented with a SAH in the right parietal sinus. In this case, we describe a hyper-homocysteinemia in a heterozygous patient for the methylenetetrahydrofolate reductase C667T mutation. Our report highlights the value of an early diagnosis of CVT, the importance of identifying possible causes that could be reversed with an appropriate treatment, and the controversy about the timing for starting anticoagulation therapy in such cases.

Keywords: Cerebral venous thrombosis; Cortical subarachnoid hemorrhage; Homocysteine.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Cerebral Angiography*
  • Cerebral Veins / pathology
  • Heterozygote
  • Humans
  • Magnetic Resonance Angiography*
  • Male
  • Methylenetetrahydrofolate Reductase (NADPH2) / genetics
  • Mutation, Missense
  • Subarachnoid Hemorrhage / complications*
  • Subarachnoid Hemorrhage / diagnostic imaging*
  • Subarachnoid Hemorrhage / genetics
  • Thrombosis / complications*
  • Thrombosis / diagnostic imaging*
  • Thrombosis / genetics

Substances

  • MTHFR protein, human
  • Methylenetetrahydrofolate Reductase (NADPH2)