Expanding targeted therapies for NSCLC

Cancer Discov. 2014 Dec;4(12):OF1. doi: 10.1158/2159-8290.CD-NB2014-161. Epub 2014 Oct 31.

Abstract

The targeted therapies dabrafenib and neratinib are being tested separately in subsets of patients with BRAF- and HER2-mutant non-small cell lung cancer. While dabrafenib shows some promise, the preliminary results for neratinib with or without temsirolimus are insufficient to determine whether patients may benefit.

Publication types

  • News

MeSH terms

  • Carcinoma, Non-Small-Cell Lung / drug therapy*
  • Carcinoma, Non-Small-Cell Lung / genetics*
  • Humans
  • Lung Neoplasms / drug therapy*
  • Lung Neoplasms / genetics*
  • Molecular Targeted Therapy*
  • Mutation