Cancer-killing CAR therapies gain speed

Cancer Discov. 2015 Jan;5(1):7. doi: 10.1158/2159-8290.CD-ND2014-013. Epub 2015 Jan 5.

Abstract

In recent clinical trials, engineered CAR T cells have yielded response rates as high as 90% in patients with leukemia. Now, scientists are working to get this therapy to market and possibly expand its use into solid tumors.

Publication types

  • News

MeSH terms

  • Humans
  • Immunotherapy*
  • Neoplasms / immunology*
  • Neoplasms / therapy*
  • Receptors, Antigen, T-Cell / genetics*
  • Receptors, Antigen, T-Cell / metabolism
  • Recombinant Fusion Proteins / genetics*
  • Recombinant Fusion Proteins / metabolism
  • T-Lymphocytes / immunology*
  • T-Lymphocytes / metabolism*

Substances

  • Receptors, Antigen, T-Cell
  • Recombinant Fusion Proteins