Primary malignant parotid epithelial neoplasm: nodal metastases and management

Curr Opin Otolaryngol Head Neck Surg. 2015 Apr;23(2):91-8. doi: 10.1097/MOO.0000000000000139.

Abstract

Purpose of review: This article presents a summary of the recent publications on the diagnosis and management of primary malignant parotid epithelial neoplasm, with special emphasis on evaluation and treatment of nodal metastases.

Recent findings: Pathologists are challenged with making a diagnosis, classification and grading of salivary gland cancers. The unpredictable behaviour of this disease has been documented by clinicians reporting aggressiveness and variations in disease patterns within a single-cancer subgroup. Surgeons have identified a high incidence of occult nodal disease both at the primary site and the neck, which has frequently been understaged both clinically and on imaging in the presurgical workup.

Summary: The significance of a high incidence of occult nodal disease both at the primary site and the neck is that a more aggressive therapeutic strategy must be directed/advised by the multidisciplinary clinical team, to the disease located in the head and neck, thus improving likely cure, preventing local and distant disease failure.

Publication types

  • Review

MeSH terms

  • Adult
  • Carcinoma / secondary*
  • Carcinoma / therapy*
  • Child
  • Humans
  • Lymphatic Metastasis
  • Neoplasm Staging
  • Parotid Neoplasms / pathology*
  • Parotid Neoplasms / therapy*