dsRNA-ended genomes in orthobunyavirus particles and infected cells

Daniel Kolakofsky

doi:10.1016/j.virol.2015.12.016

dsRNA-ended genomes in orthobunyavirus particles and infected cells

Virology. 2016 Feb:489:192-3. doi: 10.1016/j.virol.2015.12.016. Epub 2016 Jan 7.

Author

Daniel Kolakofsky¹

Affiliation

¹ Department of Microbiology and Molecular Medicine, University of Geneva School of Medicine, CMU, 9 Avenue de Champel, 1211 Geneva, Switzerland. Electronic address: Daniel.Kolakofsky@unige.ch.

PMID: 26773379
DOI: 10.1016/j.virol.2015.12.016

Abstract

dsRNA-ended genome RNPs accumulate during LaCrosse bunyavirus infection. The possible significance of these dsRNA structures for orthobunyavirus replication and survival are discussed.

Keywords: Bunyavirus; DsRNA; Genome RNPs.

Publication types

Letter

MeSH terms

Bunyaviridae Infections / virology*
Genome, Viral
Humans
Orthobunyavirus / genetics
Orthobunyavirus / physiology
RNA, Double-Stranded / genetics
RNA, Double-Stranded / metabolism*
RNA, Viral / genetics
RNA, Viral / metabolism*
Virus Replication

Substances

RNA, Double-Stranded
RNA, Viral