Tumors of the lacrimal gland

Semin Diagn Pathol. 2016 May;33(3):156-63. doi: 10.1053/j.semdp.2015.10.002. Epub 2015 Oct 9.

Abstract

Tumors of the lacrimal gland comprise a wide spectrum, of which the most common demonstrate epithelial and lymphoid differentiation. The diagnosis of lacrimal gland tumors depends primarily on histological evaluation, as do the choice of treatment and prognosis. For some lacrimal gland neoplasms, such as adenoid cystic carcinoma, the outlook is grave. Optimal treatment for several lacrimal gland tumors is also a matter of controversy. However, recent progress has been made in the molecular and genetic understanding of tumorigenesis for such lesions. This article presents an overview of the histopathology of lacrimal gland tumors, together with their epidemiological features, clinical characteristics, and treatment strategies.

Keywords: Epithelial tumors; Lacrimal gland tumors; Lymphoid tumors; Mesenchymal tumours; Ophthalmic pathology.

Publication types

  • Review

MeSH terms

  • Eye Neoplasms / pathology*
  • Humans
  • Lacrimal Apparatus / pathology*
  • Neoplasms, Glandular and Epithelial / pathology*