Venous thromboembolism in cancer patients: risk assessment, prevention and management

Future Cardiol. 2016 Mar;12(2):221-35. doi: 10.2217/fca.15.87. Epub 2016 Feb 26.

Abstract

Thrombosis and thromboembolic events contribute to significant morbidity in cancer patients. Venous thrombosis embolism (which includes deep vein thrombosis and pulmonary embolism) accounts for a large percentage of thromboembolic events. Appropriate identification of cancer patients at high risk for venous thromboembolism and management of thromboembolic event is crucial in improving the quality of care for cancer patients. However, thromboembolism in cancer patients is a complex problem and the management has to be tailored to each individual. The focus of this review is to understand the complex pathology, physiology and risk factors that drive the process of venous thrombosis and embolism in cancer patients and the current guidelines in management.

Keywords: VTE prevention; guidelines-based VTE management; risk stratification; thrombosis in cancer patients.

Publication types

  • Review

MeSH terms

  • Humans
  • Neoplasms / complications*
  • Neoplasms / pathology
  • Neoplasms / physiopathology
  • Risk Assessment
  • Venous Thromboembolism / diagnosis
  • Venous Thromboembolism / etiology*
  • Venous Thromboembolism / therapy*